Integrated Device for Circulating Tumor Cell Capture, Characterization, and Lens-Free Microscopy

Abstract

For this project, we aim to develop and integrate two highly innovative new technologies to capture and characterize circulating tumor cells found in the blood of patients with breast cancer. The first is a highly innovative cell capture technology for blood and other body fluids based on a microfluidics microchip technology. The second is an entirely new imaging technology based on a lens-free holographic scanning. The resulting device will ultimately be clinically relevant, cost-effective, straight forward, and portable. It will address a significant technology deficiency in current circulating tumor cell analysis at the clinical level that is cost-effective and high-throughput.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2011
Accession Number
ADA550879

Entities

People

  • Changhuei Yang

Organizations

  • California Institute of Technology

Tags

Communities of Interest

  • Air Platforms
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Air Force
  • Breast Cancer
  • California
  • Electrical Engineering
  • Focal Planes
  • High Resolution
  • Holograms
  • Holographic Optical Elements
  • Laser Spots
  • Lasers
  • Light Sources
  • Microscopy
  • Neoplasms
  • Optics
  • Scanning
  • Two Dimensional
  • United States

Fields of Study

  • Medicine

Readers

  • Molecular and genetic basis of cancer.
  • Nanoscale Plasmonic Nanotechnology
  • Optical Physics and Photonics.