Guidelines for the Prevention of Infections Associated With Combat-Related Injuries: 2011 Update (Executive Summary)

Abstract

Despite advances in resuscitation and surgical management of combat wounds, infection remains a concerning and potentially preventable complication of combat-related injuries. Interventions currently used to prevent these infect ions have not been either clearly defined or subjected to rigorous clinical trials. Current infection prevention measures and wound management practices are derived from retrospective review of wartime experiences, from civilian trauma data and from in Vitro and animal data. This update to the guidelines published in 2008 incorporates evidence that has become available since 2007. These guidelines focus on care provided within hours to days of injury, chiefly within the combat zone to those combat-injured patients with open wounds or burns. New in this update are a consolidation of antimicrobial agent recommendations to a backbone of high-dose cefazolin with or without metronidazole for most postinjury indications and recommendations for redosing of antimicrobial agents use of negative pressure wound therapy, and for oxygen supplementation in flight.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2011
Accession Number
ADA552422

Entities

People

  • Clinton K. Murray
  • Duane R. Hospenthal
  • Jason H. Calhoun
  • John M. Cho
  • Jon C. Clasper
  • Kevin K Chung
  • Leopoldo C. Cancio
  • Marcus H. Colyer
  • R. B. Bell
  • Romney C. Andersen

Organizations

  • San Antonio Military Medical Center

Tags

DTIC Thesaurus Topics

  • Anti-Infective Agents
  • Combat Injuries
  • Debridement
  • Dermatologic Agents
  • Health Services
  • Infection
  • Medical Personnel
  • Patient Care
  • Therapy
  • Thoracic Injuries
  • Wound Infections
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Defense Financial Management and Audit.
  • Immunology
  • Neurotrauma and Rehabilitation Medicine.