"Point of Injury" Sampling Technology for Battlefield Molecular Diagnostics

Abstract

The overall aim of this project is to develop a diagnostic field test that can be used to detect traumatic brain injury and late stage shock from a drop of blood taken from a finger stick. For Phase I, the goal is to develop the sample processing technology that takes blood from a finger stick and produces purified and concentrated plasma, within which we can detect rare blood-borne biomarkers. The technology should enable a portable system that can be set up in a remote location and enable clinical diagnosis of a variety of conditions. The system will be accompanied with disposable cassettes that are specific to the test.

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Document Details

Document Type
Technical Report
Publication Date
Nov 14, 2011
Accession Number
ADA552943

Entities

People

  • Bernardo Cordovez
  • Robert Hart

Tags

Communities of Interest

  • Advanced Electronics
  • Sensors
  • Weapons Technologies

DTIC Thesaurus Topics

  • Battlefields
  • Blood
  • Blood Cells
  • Brain Injuries
  • Chemistry
  • Detection
  • Detectors
  • Fabrication
  • Failure Mode And Effect Analysis
  • First Responders
  • Flow Rate
  • Fluids
  • Measurement
  • Medical Personnel
  • Metallic Nanoparticles
  • Raman Spectroscopy
  • Surface Chemistry

Readers

  • Molecular Genetics
  • Neurotrauma and Rehabilitation Medicine.
  • Toxicology/Environmental Toxicology