VITAL: Vanguard Investigations of Therapeutic Approaches to Lung Cancer

Abstract

The VITAL Research Program will provide a better understanding of the cellular and molecular processes that drive lung tumorigenesis so that an accurate risk model for recurrence and/or the development of the secondary primary tumor can be developed, and the biologic agents most effective in reducing these events in the group of high-risk patients can be identified. We will be incorporating retrospective clinical trial specimens to develop our risk model and validating it with specimens collected from our Vanguard study. The research projects are proceeding well as proposed, producing valuable findings with cell lines, and will validate these results using the clinical samples obtained from the VITAL trials in the coming years.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2011
Accession Number
ADA553116

Entities

People

  • David M Stewart
  • Edward Kim
  • Ignacio Wistuba
  • J. J. Lee
  • Reuben Lotan
  • Waun K. Hong

Organizations

  • University of Texas at Austin

Tags

DTIC Thesaurus Topics

  • Carcinoma
  • Cell Physiological Processes
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • Medical Personnel

Fields of Study

  • Medicine

Readers

  • Computational Modeling and Simulation
  • Molecular Biology and Genetics
  • Oncology and Biomarker-Based Cancer Detection.