Osteoclast Inhibitory Peptide-1 Therapy for Paget's Disease

Abstract

Paget's disease of bone (PDB) is a chronic focal skeletal disorder that affects 2-3% of the population over the age of 60 yr. PDB is inherited as an autosomal dominant trait with genetic heterogeneity and characterized by highly localized areas of bone turnover with increased osteoclast (OCL) actively followed by an exaggerated osteoblast response.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2011
Accession Number
ADA553287

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  • Sakamuri Reddy

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