Targeting Cell Surface Proteins in Molecular Photoacoustic Imaging to Detect Ovarian Cancer Early
Abstract
Our idea is to apply a series of novel techniques to identify the reagents needed to move imaging technology forward into the clinic. While molecular imaging strategies are now approaching the resolution required to detect ovarian cancer in an early curable stage, specific imaging probes are not currently available and are urgently needed to realize the potential of imaging for ovarian cancer early detection. To address this challenge we will conduct for the first time a comprehensive, comparative survey of the surface proteome of serous ovarian cancer and human ovarian surface epithelial cells in order to select and validate ovarian cancer specific surface proteins for use as targets in molecular photoacoustic imaging, an especially promising imaging strategy for ovarian cancer early detection.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2011
- Accession Number
- ADA553529
Entities
People
- Charles W. Drescher
Organizations
- Fred Hutchinson Cancer Center