Laser Application on Orthopaedic Bone Repair

Abstract

The goal of this project is to improve the treatment of bone defect by leveraging a rat cortical bone allograft model and Er:YAG laser currently used in the dental field. To achieve this goal we will test the hypothesis that: 1) segmental bone defects treated with Er:YAG laser irradiation will form significantly more and stronger cortical bone allograft incorporation; and 2) segmental bone defects treated with cortical bone allograft pre-conditioned by Er:YAG laser will form significantly more and stronger cortical bone allograft incorporation. The project is currently in progress and definitive results await further analysis. However, post-operative observations and body weight gain indicated there were no complications such as allergic reactions, abscesses or infections. Body weight gain in the laser-treated animals was similar to that in non-laser treated animals during the healing period. These results showed a successful feasibility of the Er:YAG laser system for the cortical bone allograft model.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2011
Accession Number
ADA553890

Entities

People

  • Amarjit S. Virdi
  • Kotaro Sena

Organizations

  • Rush University

Tags

DTIC Thesaurus Topics

  • Acquisition
  • Agreements
  • Biomedical Research
  • Body Weight
  • Department Of Defense
  • Infection
  • Intellectual Property
  • Laboratory Animals
  • Laser Applications
  • Lasers
  • Medical Personnel
  • Observation
  • Patent Applications
  • Surgery
  • Two Dimensional
  • Wound Infections
  • Yag Lasers

Readers

  • Immunology and Pathology
  • Neurotrauma and Rehabilitation Medicine.
  • Optical Physics and Photonics.

Technology Areas

  • Directed Energy