Convection-Enhanced Delivery (CED) in an Animal Model of Malignant Peripheral Nerve Sheath Tumors and Plexiform Neurofibromas

Abstract

Due to delays in obtaining regulatory approval from both our own IACUC and the DOD, we were unable to begin our study until very recently. Despite the delays, we have made progress in establishing the cell lines necessary for the study to proceed, characterization of the cell lines, and further developing and establishing surgical methods for sciatic implantation and convection enhanced delivery within the tumors. Despite the delays, we are confident that we will be able to complete the proposed work within the time-frame initially proposed, with an accelerated schedule.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2011
Accession Number
ADA554194

Entities

People

  • Kaleb Yohay

Organizations

  • Cornell University

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Catheters
  • Cell Line
  • Cells
  • Data Analysis
  • Department Of Defense
  • Dermatologic Agents
  • Growth Factors
  • Neoplasms
  • Nerves
  • Nervous System
  • Neuromuscular Diseases
  • Peripheral Nervous System
  • Sciatic Nerve
  • Surgery
  • Therapy
  • Xenografts

Readers

  • Clinical Trial Research.
  • Molecular and Cellular Biology
  • Systems Analysis and Design