Exploring the Mechanism of Biomolecule Immobilization on Plasma-Treated Polymer Substrates

Abstract

An electron beam-generated plasma source developed at NRL was used to modify polystyrene microtitre plates. A combination of complementary surface analytical and biochemical techniques was applied to evaluate the relationship between the biotic and abiotic layers, with particular emphasis on the efficiency of the preparation of polymer surfaces and its effectiveness for bioimmobilization. We conclude that the development of novel interface materials with superior transducing capabilities is dependent on the deeper understanding of the complex physicochemical, nanoscale interactions between the substrate surface and the biological components attached to it.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2012
Accession Number
ADA555840

Entities

People

  • C. R. Taitt
  • E. H. Lock
  • J. Wojciechowski
  • S. H. North
  • Scott G. Walton

Organizations

  • United States Naval Research Laboratory

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Biomolecules
  • Charged Particles
  • Chemistry
  • Dielectric Polymers
  • Electron Beams
  • Electron Energy
  • Electrons
  • Energy
  • Ionization
  • Materials
  • Mechanical Properties
  • Military Research
  • Polymers
  • Roughness
  • Substrates
  • Surface Energy
  • Surface Roughness

Readers

  • Nanoscale Plasmonic Nanotechnology
  • Plasma Physics / Magnetohydrodynamics
  • Surface Coatings Technology.

Technology Areas

  • Directed Energy
  • Microelectronics