Anticipating the Species Jump: Surveillance for Emerging Viral Threats

Abstract

Emerging infectious diseases (EID) pose international security threats because of their potential to inflict harm upon humans, crops, livestock, health infrastructure, and economies. Some zoonotic (animal) viruses pose unique challenges because of their ability to infect new host species. For example, influenza and human immunodeficiency viruses originally infected animals, but subsequent mutations enabled these viruses to jump to new human hosts. Zoonotic disease surveillance is typically triggered after animal pathogens have infected humans. Yet, what might be achieved by surveillance that precedes human infection? Can it be done? How? Where? By whom? On 3-4 December 2009, the Advanced Systems and Concepts Office of the Defense Threat Reduction Agency (DTRA-ASCO) convened a workshop of experts to conceptualize the future of predictive surveillance for viruses that jump from animals to infect humans.Virologists, ecologists, and computational biologists from academia, US Government and nongovernmental organizations discussed opportunities as well as obstacles to prediction of species jumps using genetic and ecological determinants from virus, host, vector and reservoir.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2010
Accession Number
ADA556992

Entities

People

  • Colin R Parrish
  • Gregory E. Glass
  • Meg L. Flanagan
  • Robin M. Bush
  • Sarah Cobey
  • Terrance J. Leighton

Organizations

  • Pennsylvania State University

Tags

DTIC Thesaurus Topics

  • Animal Diseases
  • Cells
  • Disease Outbreaks
  • Geography
  • Health Services
  • Human Population
  • Infectious Diseases
  • Proteins
  • Public Health
  • Rna Viruses
  • Rodents
  • Teamwork
  • United States
  • Virion
  • Virus Diseases
  • Viruses
  • Wildlife

Readers

  • Defense Technology Research and Development.
  • Infectious Disease/Epidemiology
  • Systems Analysis and Design

Technology Areas

  • Biotechnology