Comparative Proteomics of Tandem Mass Spectrometry Analyses for Bacterial Strains Identification and Differentiation

Abstract

Bacterial proteome represents the collection of functional and structural proteins that are present in the cell. The bacterial proteome consists of diverse classes of proteins with different cellular functions. Overall, the protein content of the cell represents the majority of the cell dry weight, which makes it an ideal cellular component to be utilized for bacterial characterization. Comparative proteomics has been widely applied to microbial identification and characterization studies through the utilization of several mass spectrometry techniques, with tandem mass spectrometry techniques proving to be effective and reliable approach. This chapter will address the utilization of comparative proteomics and the application of tandem mass spectrometry in the identification and differentiation of bacterial strains.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 2012
Accession Number
ADA557726

Entities

People

  • A. P. Snyder
  • Alan W. Zulich
  • Mary M. Wade
  • Michael F. Stanford
  • Rabih E. Jabbour
  • Samir V. Deshpande

Organizations

  • Edgewood Chemical Biological Center

Tags

DTIC Thesaurus Topics

  • Bacteria
  • Bacterial Proteins
  • Cell Membrane
  • Chemistry
  • Databases
  • Electrospray Ionization
  • Identification
  • Liquid Chromatography
  • Mass Spectra
  • Mass Spectrometry
  • Membrane Proteins
  • Microbiology
  • Microorganisms
  • Proteins
  • Proteomics
  • Spectrometry
  • Two Dimensional

Fields of Study

  • Biology
  • Chemistry

Readers

  • Analytical Chemistry
  • Molecular Genetics
  • Systems Analysis and Design

Technology Areas

  • Biotechnology