Breast Cancer Endothelial Cell Calcium Dynamics Using Two-Photon Microscopy

Abstract

Control murine liver endothelial cells and murine breast tumor endothelial cells were successfully isolated and plated for the imaging and flow cytometry experiments. I have found interesting differences between normal and tumor endothelial cells well worth further studying. More specifically, I have found that the response of tumor endothelial cells to VEGF is the same regardless of whether or not they have been serum-starved. Also receptor densities of VEGFR-1 and -2 differ between normal and breast tumor ECs.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2012
Accession Number
ADA558870

Entities

People

  • Javier Lapeira

Organizations

  • University of Rochester

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Engineering
  • Biomedical Research
  • Breast Cancer
  • Cancer
  • Cell Line
  • Cells
  • Department Of Defense
  • Electronic Mail
  • Endothelial Cells
  • Engineering
  • Fluorescence
  • Growth Factors
  • Inhibition
  • Instructions
  • Intensity
  • Neoplasms

Fields of Study

  • Biology

Readers

  • Oncology (Cancer Research).