Epidemiological Study of Mild Traumatic Brain Injury Sequelae Caused by Blast Exposure During Operations Iraq Freedom and Enduring Freedom
Abstract
Accomplishments include initial and ongoing IRB review & approval of all initial submissions, protocol amendments, recruitment advertisements, serious adverse effects, and off-site recruitment activities. We continue to submit to both McGuire and WRAMC IRBs. During Year-3, Camp Lejeune USMC Base was added as a recruitment site. The appropriate US Navy IRB agreed to accept the findings of the WRAMC IRB. All research assistant positions were filled during this reporting period. Study procedures, recruitment, data management, and analyses have been refined through meetings, reviews, consultations, and through lessons learned during completed data collection efforts to date. Subject recruitment and protocol implementation commenced at the VAMC site in 12/08 and at Fort Lee Army Base in 6/09. Through 8/31/11, one hundred sixty one (161) subjects have been accrued (with 152 enrolled) following screen failures) through Polytrauma Network Site Clinic screening, Polytrauma Inpatient Rehabilitation Center, recruitment letters mailed, radio advertisements, posters in the clinics, and on-site enrollment at Fort Lee, VA, USMC Base Camp Lejeune, and USMC Base Quantico. Pending data analysis, most subjects appear to meet symptom criteria for PCS. Conclusions to Date: Enrollment has commenced and continues. Study personnel continue to work with the military partners to improve access to post-deployed service members. The accumulating sample should also be suitable for intervention trials under development. To ensure a sample representative of the target population, we are addressing means to improve access to active duty service members at additional recruitment sites while pursuing expanding outreach to those at existing partner sites.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2011
- Accession Number
- ADA559124
Entities
People
- Jerome R. Heimiller
- William C. Walker