MicroRNAs: Novel Breast Cancer Susceptibility Factors in Caucasian and African American Women

Abstract

So far, we have completed the genotyping analysis in 800 Caucasian and 800 African American breast cancer patients, and 800 Caucasian and 800 African American healthy controls. A total of 275 SNPs were analyzed, including 112 SNPs in the microRNA genes, and 163 SNPs in microRNA processing genes. We have identified several SNPs in microRNA processing genes and microRNA genes are associated with breast cancer risk in either Caucasian Americans or African Americans.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2011
Accession Number
ADA561086

Entities

People

  • Hua Zhao

Organizations

  • Health Research, Incorporated

Tags

DTIC Thesaurus Topics

  • Abstracts
  • African Americans
  • Biomedical Research
  • Biospecimens
  • Breast Cancer
  • Caucasians
  • Department Of Defense
  • Electronic Mail
  • Genes
  • Genetic Variation
  • Governments
  • Information Operations
  • National Governments
  • Neoplasms
  • Standards

Fields of Study

  • Biology

Readers

  • Molecular and genetic basis of cancer.