Characterizing the Behavioral Effects of Nerve Agent-induced Seizure Activity in Rats: Increased Startle Reactivity and Perseverative Behavior

Abstract

The development and deployment of next-generation therapeutics to protect military and civilian personnel against chemical warfare nerve agent threats require the establishment and validation of animal models.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2012
Accession Number
ADA561208

Entities

People

  • Jeffrey L. Langston
  • Linnzi K. Wright
  • Lucille A. Lumley
  • Nick Connis

Organizations

  • United States Army Medical Research Institute of Chemical Defense

Tags

DTIC Thesaurus Topics

  • Biochemistry
  • Chemical Warfare
  • Chemical Warfare Agents
  • Chemical Weapons
  • Civilian Personnel
  • Demographic Cohorts
  • Deployment
  • Nerve Agents
  • Pharmacology
  • Printing
  • Reactivities
  • Therapy
  • Validation
  • Warfare

Fields of Study

  • Biology
  • Psychology

Readers

  • Computational Fluid Dynamics (CFD)
  • Neurotoxicology
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.