Early Support of Intracranial Perfusion
Abstract
This report represents the second year in a multi-year effort to improve outcomes in patients with traumatic brain injury (TBI). This project utilizes human and animal models in an effort first to identify what factors are important in determining outcome from TBI and secondly to test new techniques in patient care. Year 1 focused on development of an infrastructure for gathering data in TBI patients, development of a protocol to advance understanding of the inflammatory process which follows TBI, and creation of a basic science model of brain trauma. Staff were hired and assigned, equipment purchased and protocols and databases developed. Year 2 has seen the implementation of two human use protocols, on-going development and testing of the Brain Resuscitation Registry (BRR) to provide structure and linkage capabilities for data collection and outcome reporting, and further development and re-formatting of the animal model sub-project. IRB protocols for year 3 projects are being developed for submission, equipment (server and computer tablets) purchased to allow the implementation of the BRR and assay kits ordered to allow the processing of specimens collected as part of the Cytokines sub-project. The basic science model was revised during Year 2 and now reflects both small and large animal models of polytrauma
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2009
- Accession Number
- ADA561374
Entities
People
- Karen Murdock
- Lisa Gettings
- Thomas Scalea
Organizations
- University of Maryland, Baltimore