Framework for Smart Electronic Health Record-Linked Predictive Models to Optimize Care for Complex Digestive Diseases

Abstract

Our major objective is to develop an electronic application capable of integrating and semantically standardizing electronic medical record (EMR) data to generate de-identified datasets populated with longitudinal clinical data drawn from diverse sources. In Year 1 of our project, we have successfully built the infrastructure to support this project. We have defined and generated the EMR-based datasets to be used for algorithm development. In year 2, we will test the ability of this tool to support predictive modeling of the outcomes of complex digestive diseases using Bayesian network (BN) analysis of the generated databases. We will further compare performance among models generated using EMR data alone and data from disease-specific clinical research repositories (with and without genetic data). In collaboration with Walter Reed Army Medical Center, we will share our data acquisition strategies and algorithmic model development. The integration of the two distinct patient populations will lay the groundwork for future data-sharing projects of mutual interest.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2012
Accession Number
ADA562320

Entities

People

  • Melissa Saul
  • Michael A. Dunn

Organizations

  • University of Pittsburgh

Tags

DTIC Thesaurus Topics

  • Acquisition
  • Algorithms
  • Bayesian Networks
  • Data Acquisition
  • Data Science
  • Databases
  • Diseases And Disorders
  • Health Care
  • Health Informatics
  • Health Services
  • Information Science
  • Information Systems
  • Infrastructure
  • Liver Diseases
  • Models
  • Predictive Modeling
  • Statistics

Readers

  • Distributed Systems and Data Platform Development
  • Medical or Health Care Field.

Technology Areas

  • AI & ML
  • Biotechnology
  • Microelectronics