Ultraviolet B Irradiance and Incidence Rates of Bladder Cancer in 174 Countries

Abstract

Smoking is the principal established cause of bladder cancer, and per capita cigarette consumption was the variable most strongly associated with bladder cancer incidence rates in this study. Incidence rates were higher in countries located at latitudes distant from the equator where UVB irradiance is low, than in countries closer to the equator, where it is high. Furthermore, UVB irradiance was independently inversely associated with incidence rates, even after controlling for smoking or per capita health expenditures. The study was to determine whether an inverse association exists between ultraviolet B irradiance (UVB) and incidence rates of bladder cancer worldwide. Further investigation is needed to confirm the associations identified in this study using observational studies of individuals. This should include research on the association of serum 25(OH)D levels with risk of bladder cancer.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 2010
Accession Number
ADA562515

Entities

People

  • Cedric F. Garland
  • Edward Doerr Gorham
  • Frank C. Garland
  • Sharif B. Mohr
  • William B. Grant

Organizations

  • Naval Health Research Center

Tags

DTIC Thesaurus Topics

  • Bladder Cancer
  • Cancer
  • Cloud Cover
  • Colon Cancer
  • Earth Sciences
  • Geography
  • Latitude
  • Neoplasms
  • Preventive Medicine
  • Topography
  • Vitamin D

Fields of Study

  • Medicine

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