A Comparison of Proximal Tibia, Proximal Humerus and Distal Femur Infusion Rates of Blood Under High Pressure Using the EX IO Intraosseous Device in the Adult Swine (Sus scrofa) Hypovolemic Model
Abstract
PURPOSE: Compare flow rates of blood administered through intraosseous (10) needle in proximal tibia and humerus, and distal femur under high pressure(>300mmHg) in adult hypovolemic (sus scrofa). METHOD:3 groups of animals; 14 per group were intubated and ventilated. Central vein and arterial lines were placed, blood was removed until MAP is 50% of baseline. An EZIO needle was inserted. Blood was reinfused under pressure. Lung samples evaluated for signs offal emboli (FE). FINDINGS:Mean infusion rate for tibia was ml/min(SD 38.5mL/min), 49mL/min(SD 45.1mL/min) for femur and 103mL/min(SD 34.1 mL/min) for humerus. Infusion rate comparison of all sites using ANOY A revealed p < 0.005. Comparing the infusion rates of humerus (103 mL/min) to femur(49mL/min) revealed a p<0.01. Comparisons of tibia with humerus and femur revealed no statistical significance. Histopath exam revealed FE were present in 100% of tibia ann, 91% of humerus ann, and 57% offemur arn. CONCLUSION: rate of IO infusion of blood through the humerus was grater than femur and tibia. FE detected in lungs of most animals.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 25, 2012
- Accession Number
- ADA563298
Entities
People
- Julio Lairet
- Vikhyat S Bebarta
Organizations
- 59th Medical Wing