Prospects for a Novel Ultrashort Pulsed Laser Technology for Pathogen Inactivation

Abstract

The threat of emerging pathogens and microbial drug resistance has spurred tremendous efforts to develop new and more effective antimicrobial strategies. Recently, a novel ultrashort pulsed (USP) laser technology has been developed that enables efficient and chemical-free inactivation of a wide spectrum of viral and bacterial pathogens. Such a technology circumvents the need to introduce potentially toxic chemicals and could permit safe and environmentally friendly pathogen reduction, with a multitude of possible applications including the sterilization of pharmaceuticals, blood products, and the generation of attenuated or inactivated vaccines.

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Document Details

Document Type
Technical Report
Publication Date
Jul 06, 2012
Accession Number
ADA563944

Entities

People

  • Juliann G Kiang
  • Kong-thon Tsen
  • Shaw-wei D. Tsen
  • Tzyy C. Wu

Organizations

  • Uniformed Services University of the Health Sciences

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anti-Infective Agents
  • Bacteria
  • Blood
  • Chemistry
  • Femtosecond Lasers
  • Gamma Rays
  • Lasers
  • Microbiology
  • Microorganisms
  • Papillomavirus Infections
  • Pathogenic Bacteria
  • Proteins
  • Pulsed Lasers
  • Raman Scattering
  • Spectra
  • Vaccines
  • Viruses

Readers

  • Infectious Disease/Epidemiology
  • Pulsed Power and Plasma Physics.
  • Systems Analysis and Design

Technology Areas

  • Biotechnology
  • Directed Energy