Lower Prediagnostic Serum 25-Hydroxyvitamin D Concentration Is Associated With Higher Risk of Insulin-requiring Diabetes: A Nested Case-Control Study

Abstract

Aims/hypothesis Low serum 25-hydroxyvitamin D [25 (OH)D] concentration may increase risk of insulinrequiring diabetes. Methods A nested case control study was performed using serum collected during 2002 2008 from military service members. One thousand subjects subsequently developed insulin-requiring diabetes. A healthy control was individually matched to each case on blood-draw date ( 2 days), age ( 3 months), length of service ( 30 days) and sex. The median elapsed time between serum collection and first diagnosis of diabetes was 1 year (range 1 month to 10 years). Statistical analysis used matched pairs and conditional logistic regression.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2012
Accession Number
ADA566961

Entities

People

  • Alina A. Burgi
  • Camillo Ricordi
  • Cedric F. Garland
  • Edward Doerr Gorham
  • Heather Hofflich
  • June J. Kim
  • Kenneth Zeng
  • Sharif B. Mohr

Organizations

  • Naval Health Research Center

Tags

DTIC Thesaurus Topics

  • Active Duty
  • African Americans
  • Breast Cancer
  • Department Of Defense
  • Diabetes
  • Ethnic Groups
  • Health
  • Health Services
  • Immune System
  • Insulin
  • Intervals
  • Laboratory Procedures
  • Medical Personnel
  • Nutrition Disorders
  • Statistical Analysis
  • Transplants
  • Vitamin D

Fields of Study

  • Medicine

Readers

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