Mechanisms of Mitochondrial Defects in Gulf War Syndrome
Abstract
Approximately 100,000 individuals have medical complaints consistent with Gulf War syndrome (GWS). Clinical manifestations of GWS are similar to those identified in Chronic Fatigue Syndrome (CFS) and mitochondrial defects are identified pathologically, metabolically, and genetically in some patients with CFS. In order to better understand and manage patients with GWS, the investigation of mitochondrial dysfunction in this syndrome is an important undertaking. During Year 3 of this grant, we have completed the validation of all laboratory testing that will be utilized and have had fifteen new subjects participate in the study. We have also been granted a no-cost extension to continue our study through July 2013. This extension will enable us to gather sufficient data to draw meaningful conclusions. The preliminary data support the hypothesis that important similarities exist between CFS and GWS patients.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2012
- Accession Number
- ADA567223
Entities
People
- John M. Shoffner
Organizations
- Georgia State University