Objective Methods to Test Visual Dysfunction in the Presence of Cognitive Impairment

Abstract

Purpose: to develop and validate objective tests to diagnose vision deficits in patients with cognitive impairment and ensure effective monitoring of their treatment. Scope: objective methods to monitor visual function include 1) the pupil light reflex, 2) light evoked potentials from the brain and from the eye and 3) purposeful eye movements to track moving targets that are resolved. Major Findings (year one): 1) a hand held pupillometer was evaluated resulting in a new chromatic stimulus and pupil test being delivered by Neuroptics which will differentiate photoreceptor from optic nerve disease, 2) a prototype, dry electrode system was evaluated and requirements fully specified with delivery expected in Year 2, 3) A Smart Eye head and ocular tracking system was implemented and evaluated, 4) a software architecture for stimulus presentation, data synchronization, and analysis was developed and completed, 5) integration of an entire ocular testing echo-system was completed that integrates visual stimulation, evoked potential recording, head/eye tracking, and pupil responses. Significance: objective tests of vision will greatly improve eye care by providing faster, lower cost testing that can be performed in remote settings and will provide a new tool for assessing innovative treatments being developed to save or restore vision.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2011
Accession Number
ADA567270

Entities

People

  • Randy H. Kardon

Organizations

  • University of Iowa

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Brain Injuries
  • Cameras
  • Cognitive Impairment
  • Department Of Defense
  • Diseases And Disorders
  • Dynamic Range
  • Electrodes
  • Electrophysiological Phenomena
  • Eye Movements
  • Frequency
  • Head (Anatomy)
  • Head Injuries
  • Light Sources
  • Medical Personnel
  • Monitors
  • Optic Nerve
  • Software Design

Fields of Study

  • Medicine

Readers

  • Aerospace Test and Evaluation
  • Vision Science/Vision Psychology/Cognitive Neuroscience.