Feasibility Study of a Novel Diet-Based Intervention for Prostate Cancer

Abstract

Our goal is to develop a practical, diet-based intervention for prostate cancer. We have implemented a randomized clinical trial of a novel dietary intervention for prostate cancer that promotes vegetable intake among prostate cancer patients who are being treated with active surveillance. As part of this trial, we are testing whether a gene fusion biomarker will predict disease progression in this patient population. During the fourth year of the funding period, I accomplished eight major tasks. First, I oversaw the accrual of 150 patients at 40 sites nationally. Second, at the San Diego VA Hospital, I completed the required IRB documentation, opened the study to accrual, and recruited 10 patients. Third, I continued to oversee study enrollment at the Moores UC San Diego Comprehensive Cancer Center. Fourth, I responded to continued administrative review of the DoD human subjects protection documents. Fifth, I continued my regular participation in the Alliance for Clinical Trials in Oncology, formerly known as the Cancer and Leukemia Group B cooperative study group, by attending meetings and participating in conference calls. Sixth, I continued to guide the study protocol through regular contact with Alliance personnel, collaborators at participating sites, and revisions to the study protocol. Seventh, I presented a formal update of the study to Alliance clinical research associates. Finally, I presented a formal update of the study to the Southwest Oncology Group leadership.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2012
Accession Number
ADA567307

Entities

People

  • J. K. Parsons

Organizations

  • University of California, San Diego

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alliances
  • Clinical Trials
  • Department Of Defense
  • Disease Attributes
  • Diseases And Disorders
  • Electronic Mail
  • Health Services
  • Hospitals
  • Intervention
  • Leadership
  • Leukemia
  • Medical Personnel
  • Neoplasms
  • Oncology
  • Prostate
  • Prostate Cancer
  • Surveillance

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Prostate Cancer Biology.