A Medical Center Network for Optimized Lung Cancer Biospecimen Banking

Abstract

The mission statement of the Lung Cancer Biospecimen Resource Network (LCBRN) states that the LCBRN will collect, annotate, store, and distribute human lung cancer biospecimens in a manner that embraces the highest ethical standards for human subjects research, that conforms to the best practices of biorepository science, and that furthers basic, translational and clinical research in the understanding, diagnosis and treatment of this disease . Year 2 of the award has been spent increasing subject enrollment at all sites, building on the informatics infrastructure to support biorepository activity, creating the web site that serves as the interface between investigators, the public and the LCBRN, and establishing a biomolecular extraction technique that allows the LCBRN to provide investigators with nucleic acids and protein instead of the tissue samples themselves. Coordinators, procurement personnel and co-PIs continue to participate in monthly LCBRN conference calls, and all Resource Sites continue to ship biospecimens for permanent banking to the LCBRN Coordinating Center at regular intervals. Although the LCBRN was initially prepared to provide samples to investigators in September 2012, sample distribution has been delayed until the Coordinating Center completes molecular extraction of previously banked and tissue specimens as recommended by the EAB.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2012
Accession Number
ADA567691

Entities

People

  • Christopher A. Moskaluk

Organizations

  • University of Virginia

Tags

DTIC Thesaurus Topics

  • Best Practices
  • Biomedical Research
  • Biorepositories
  • Biospecimens
  • Blood
  • Cancer
  • Diseases And Disorders
  • Extraction
  • Infrastructure
  • Lung Cancer
  • Medical Personnel
  • Neoplasms
  • Networks
  • Nucleic Acids
  • Procurement
  • Quality Control
  • Websites

Readers

  • Clinical Trial Research.
  • Oncology and Biomarker-Based Cancer Detection.

Technology Areas

  • Biotechnology