Detection of Xenotropic Murine Leukemia Virus-Related Virus (XMRV) in Gulf War Illness: Role in Pathogenesis or Biomarker?

Abstract

The purpose of this project is to evaluate patients with Gulf War illness (GWI) for pathogens and potential biomarkers. The original proposed aim of this study was to establish the prevalence of a newly identified infections retrovirus in individuals with GWI; however, subsequent to the award of this proposal, further reports determined that the possibility of this virus as a human pathogen was highly unlikely. Therefore, a request was made to amend the original proposal and broaden its scope to identify any pathogen and potential biomarkers in GWI. Upon receiving DOD approval of this modification, a new human subject protocol was submitted to the University of Nevada, Reno (UNR) Institutional Review Board (IRB). The protocol has been approved by the UNR IRB, VA Sierra Nevada Health Care System Research and Development Department, and the U.S. Army Medical Research and Materiel Command, Office of Research Protections, Human Research Protection Office. At this time, study subject recruitment and enrollment is in process.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2012
Accession Number
ADA567836

Entities

People

  • Vincent C. Lombardi

Organizations

  • University of Nevada, Reno

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biological Markers
  • Biomedical Research
  • Brain Injuries
  • Chronic Fatigue Syndrome
  • Computer Programs
  • Culture Techniques
  • Data Analysis
  • Health Care
  • Health Services
  • Infection
  • Institutional Review Board
  • Medical Personnel
  • Muscular Diseases
  • Therapy
  • Viruses

Readers

  • Clinical Trial Research.
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Molecular and genetic basis of cancer.