Influencing upon Mammalian Radioresistance with Biologically Active Drug Respistim Plus

Abstract

Radiobiology is a medical knowledge, which studies ionizing radiation and its influence over the human body. Military radiobiology investigates care to soldiers and civil population after radiation exposure. Acute radiation syndrome and its treatment are the main topics of military radiobiology research. These are the three main trends in Bulgarian military radiobiology: Keeping under control the first reaction after acute radiation exposure; Searching and investigating de novo synthesized chemical materials; Stem cells investigation and its clinical applications. Over the past years different biological substances are applied with success. Protection of the hematopoietic and immune systems is a critical area for restoring organism after irradiation. Some radioprotective characteristics of biologically substances, vitamins and essential elements are established. Aim of the study: To determine radioprotective effect of Bulgarian drug Respistim plus -- a mixture of lyophilized bacterial strains in combination with vitamins and essential elements on the proliferation and migration of hematopoietic stem cells, levels of white blood cells and increased 30 days survival after irradiation.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2009
Accession Number
ADA568521

Entities

People

  • I. Kindekov
  • M. Aljakov
  • P. Petrunov
  • V. Vasilieva

Organizations

  • NATO Science and Technology Organization

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Blood
  • Blood Cells
  • Bone Marrow
  • Bone Marrow Cells
  • Cells
  • Dose Rate
  • Factor Analysis
  • Free Radicals
  • Fungi
  • Gamma Rays
  • Ionizing Radiation
  • Laboratory Animals
  • Leukocytes
  • Lymphatic System
  • Military Operations
  • Stem Cells

Readers

  • Immunology
  • Molecular Biology and Genetics
  • Oncology (Cancer Research).

Technology Areas

  • Biotechnology