Sealing Penetrating Eye Injuries with Photoactivated Bonding
Abstract
The purpose of this report is to develop a light-activated technology (called PTB) with the potential to decrease vision loss and ocular complications in warfighters sustaining penetrating eye injuries. Scope: To compare light-activated bonding of amnion to direct sealing of penetrating cornea wounds, to evaluate photobonding for puncture wounds in sclera, and to evaluate safety of photobonding to the iris. Major findings: Identified the treatment parameters for rapidly and strongly sealing amniotic membrane over scleral puncture wounds. Demonstrated that photobonding amion effectively sealed wounds spanning the cornea sclera. Determined that sealing penetrating cornea wounds using a dye-stained amniotic membrane patch and green light is superior to direct photo-activated bonding of the wound walls. Established that the green light parameters used to seal amnion over cornea wounds are below the threshold for thermal damage to the iris.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 2012
- Accession Number
- ADA568974
Entities
People
- Irene E. Kochevar
Organizations
- Massachusetts General Hospital