Therapeutics for Regeneration of Fully Functional Auditory Outer Hair Cells

Abstract

To characterize the regenerative capacity of SCs in mice after noise-induced damage and transient or permanent inactivation of p1 61nk4a, and assess the ability of Atoh1 to transdifferentiate SCs into HCs after noise-induced damage in mice.

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Document Details

Document Type
Technical Report
Publication Date
Sep 27, 2012
Accession Number
ADA569196

Entities

People

  • Jian Zuo

Tags

DTIC Thesaurus Topics

  • Department Of Defense
  • Determinants (Mathematics)
  • Ear
  • Genetic Structures
  • Health Services
  • Hearing Disorders
  • Hearing Loss
  • Hospitals
  • Information Operations
  • Maturation
  • Military Research
  • Molecules
  • Small Molecules
  • Standards
  • Technology Transfer
  • Therapy
  • Transcription Factors

Readers

  • Auditory Neuroscience/Auditory Physiology.
  • Molecular and Cellular Biology