Mammographic Breast Density in a Cohort of Medically Underserved Women
Abstract
The purpose of this HBCU/MI Partnership Training Award is to train Meharry Medical College (MMC) faculty to conduct independent breast cancer research by collaborating with faculty from Vanderbilt University Medical Center (VUMC). Three MMC faculty will undergo intensive training supervised by three VUMC faculty during year 1 with additional training taking place in subsequent years. To reinforce training, faculty from MMC and VUMC will conduct a case-control study of mammographic breast density to investigate its association with obesity and insulin resistance in years 2 through 4. Cases (n=150) whose breasts are in the upper quartile of breast density and controls (n=850) whose breast are in the lowest three quartiles of breast density, will be recruited from the MMC Center for Women s Health Research which serves a medically underserved population. Specific aims are: 1) to assess mammographic breast density through digital mammograms; for a sample of women we will also assess mammographic breast density through film mammograms to determine the diagnostic accuracy of digital versus film mammogram, 2) to obtain information on breast cancer risk factors including health literacy, and to collect anthropometric measurements and fasting blood, 3) to assay blood for select hormones and growth factors, 4) to perform statistical analyses to determine the associations between obesity and insulin resistance and mammographic breast density, and 5) to evaluate patients ability to understand their mammogram findings as they are explained by their medical provider.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2012
- Accession Number
- ADA569280
Entities
People
- Maureen Sanderson
Organizations
- Meharry Medical College