Rapid Parallel Screening for Strain Optimization

Abstract

Progress has been made on identifying biosensors that will be used to report on the fermentation yields of industrially relevant biological compounds. Screening of the desired chemicals has been completed. Microbes that can utilize these compounds as their sole carbon source have been isolated and archived. Genomic DNA from 97 isolates has been prepared for sequencing. Sixty-nine samples are currently in the sequencing queue but were delayed by about a month because the manufacturer had backordered library construction kits. These materials have now arrived and sequence should be available within one month.

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Document Details

Document Type
Technical Report
Publication Date
Feb 19, 2013
Accession Number
ADA573778

Entities

People

  • Chuck Merryman
  • Tony Yee

Organizations

  • J. Craig Venter Institute

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomolecules
  • Biosensors
  • Cell Physiological Processes
  • Construction
  • Contracts
  • Data Sets
  • Department Of Defense
  • Detectors
  • Engineering
  • Fermentation
  • Information Operations
  • Materials
  • Micro-Machines
  • Optimization
  • Standards
  • Synthetic Biology
  • Transcription Factors

Readers

  • Clinical Trial Research.
  • Logistics and Supply Chain Management.
  • Molecular Genetics

Technology Areas

  • Biotechnology