Application of Quantitative Phosphorous Nuclear Magnetic Resonance Spectroscopy to Chemical Warfare Agents

Abstract

This report outlines the development of an inverse-gated phosphorous nuclear magnetic resonance (NMR) spectroscopy method for determining the purity of chemical warfare agents using reference standards contained within a glass stem coaxial insert. The stem coaxial insert prevents any possible reaction of the reference standard and analyte by segregating the two solutions. The method was determined to be accurate to 1.1% and was employed to determine the purity of the V-series nerve agent VX using proton-decoupled pulse parameters. The method was found to be equal to or better than modern chromatographic techniques in terms of precision, accuracy and analysis time. The operational simplicity of this method enables both quantitative and qualitative information to be rapidly gleaned from a single sample.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2012
Accession Number
ADA575274

Entities

People

  • Nathan W. Mcgill

Organizations

  • Defence Science and Technology Group

Tags

Communities of Interest

  • Space

DTIC Thesaurus Topics

  • Accuracy
  • Acquisition
  • Australia
  • Chemical Shifts
  • Chemical Warfare
  • Chemical Warfare Agents
  • Data Sets
  • Magnetic Resonance
  • Nerve Agents
  • Nuclear Magnetic Resonance
  • Precision
  • Protons
  • Quantum Properties
  • Resonance
  • Spectroscopy
  • Standards
  • Warfare

Readers

  • Analytical Chemistry
  • Electrical Engineering
  • Systems Analysis and Design