Photoacoustic Imaging of Epilepsy

Abstract

This research is aimed at developing a new imaging approach, called Photoacoustic tomography (PAT) , for non-invasively tracking dynamical changes during seizure occurrence. The project will develop imaging hardware and software, and conduct phantom/in vivo experiments to achieve the proposed goals. During the fourth year of this project, We have developed and validated a rat model of temporal lobe epilepsy. We have performed extensive in vivo experiments to achieve concurrent EEG and PAT recordings. Interesting results are obtained that may be significant for seizure prediction and for neurovascular coupling studies. We have designed and constructed a light-weighted animal/transducer interface that can be used for chronic monitoring of freely moving animals.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2013
Accession Number
ADA576914

Entities

People

  • Huabei Jiang

Organizations

  • University of Florida

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Arteries
  • Brain
  • Detection
  • Detectors
  • Diseases And Disorders
  • Epilepsy
  • Medical Personnel
  • Neuroimaging
  • Neurosciences
  • Photoacoustic Tomography
  • Seizures
  • Tomography

Fields of Study

  • Medicine

Readers

  • Acoustical Oceanography.
  • Canadian European Scientific Immigration and Epilepsy Clearance Studies
  • Medical Imaging.