Synthesis and Characterization of Antimicrobial Nanomaterials

Abstract

The work describes how understanding fundamental biological and biophysical phenomena can be used to develop rational biotechnology solutions for Air Force requirements. Particular emphasis throughout is the integration of catalytically active biomolecules with support matrices and the utilization of these hybrid materials for development of decontamination treatments and self-sanitizing materials. Specific objectives are i) to understand the relationship between protein template molecules and metal-oxide nanoparticles, ii) define the bacteriolytic mechanism for enzymes immobilized in metal-oxide nanoparticles and iii) to evaluate antimicrobial activity from combinations of bacteriolytic hydrolases and antimicrobial peptides.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2013
Accession Number
ADA581255

Entities

People

  • D. M. Eby
  • Glenn R. Johnson
  • Heather R. Luckarift
  • Karen E. Farrington
  • Randi N. Tatum

Organizations

  • Universal Technology Corporation (United States)

Tags

DTIC Thesaurus Topics

  • Air Force
  • Air Force Research Laboratories
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Chemistry
  • Coatings
  • Composite Materials
  • Fungi
  • Infection
  • Materials
  • Materials Processing
  • Materials Science
  • Metal Oxide Nanoparticles
  • Metallic Nanoparticles
  • Nanoparticles
  • Pathogenic Bacteria
  • United States

Readers

  • Molecular and Cellular Biochemistry
  • Systems Analysis and Design

Technology Areas

  • Biotechnology