Advanced MRI in Blast-related TBI

Abstract

The purpose of the research effort was to test two advanced MRI methods, DTI and resting-state fMRI, in active-duty military blast-related TBI patients acutely after injury and correlate findings with TBI-related clinical outcomes 6-12 months later. The goal was to determine whether these methods may add clinically useful predictive information following traumatic brain injury that could be of assistance in standardizing diagnostic criteria for TBI, making return-to-duty triage decisions, guiding postinjury rehabilitation, and developing novel therapeutics. The overarching hypothesis guiding this project is that traumatic axonal injury is a principal cause of impaired brain function following blast-related TBI.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2012
Accession Number
ADA581398

Entities

People

  • David L. Brody

Organizations

  • Washington University in St. Louis

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Brain
  • Brain Injuries
  • Health Services
  • Medical Personnel
  • Neurosciences
  • Three Dimensional
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Instructional Design and Training Evaluation.
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.