Nanoengineered Drug Combinations for Breast Cancer Treatment
Abstract
Nanoparticles can be used to enhance the efficacy of chemotherapeutic drugs while minimizing their side effects. This project aims to utilize nanoparticles for effective delivery of two therapeutic agents. In particular, we aim to use two breast cancer drugs which enhance each other's efficacy (synergistic drugs), and use them as a model drug pair for the development of a novel dual-drug nano-therapeutic system. The research to date on the project has been focused on screening and identification of drug combinations that exhibit synergistic effect in vitro. This report summarizes these studies and the progress to date.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 2012
- Accession Number
- ADA581573
Entities
People
- Samir Mitragotri
Organizations
- University of California, Santa Barbara