Bioinformatic Tools for Metagenomic Analysis of Pathogen Backgrounds and Human Microbial Communities

Abstract

Metagenomics is a new area of research that generates large numbers of DNA sequences from bulk extraction of complex microbial communities. This is being done to understand the natural flora of the environment as well as the normal communities in the human body, which are thought to inhibit infections by both severe and opportunistic pathogens In year 2, we began development of a 16S rRNA database (Task 2 Subtask a), and developed additional tools exporting to/charting in Excel (Task 1 Subtask e). We also began development of tools interfacing with GreenGenes (Task 2 Subtask c). The software developed for Task 1, Subtask e and Task 2, Subtask c, are found in the appendices.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2010
Accession Number
ADA581677

Entities

People

  • Stephen Beckstrom-sternberg

Organizations

  • Translational Genomics Research Institute

Tags

DTIC Thesaurus Topics

  • Actinobacteria
  • Bacteria
  • Bacterial Infections
  • Biological Sciences
  • Data Sets
  • Databases
  • Flavobacteriaceae
  • Fungi
  • Fusobacteria
  • Human Body
  • Microbiology
  • Microbiomes
  • Pathogenic Bacteria

Fields of Study

  • Biology

Readers

  • Database Systems and Applications
  • Microbial Pathology
  • Technical Research and Report Writing.

Technology Areas

  • Biotechnology