Veno-venous Extracorporeal CO2 Removal: Can We Reduce Dependence on Mechanical Ventilation During En-route Care?

Abstract

Casualties with lung failure are mechanically ventilated during aero-medical evacuation to the continental USA. Positive-pressure mechanical ventilation is potentially injurious to the lung. Consequences of contemporary lung-protective strategies may include cardiovascular instability, use of high fraction of inspired O2, hypoventilation, hypercarbia, and acidosis. These effects may complicate patient management, motivating a search for better lung-replacement approaches. We investigated the ability of a novel extracorporeal veno-venous CO2 removal (V2CO2R) device to reduce minute ventilation (MV) while maintaining normocarbia. Our goal was to explore the potential utility of this technology to reduce dependence on mechanical ventilation during en-route care.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2010
Accession Number
ADA582063

Entities

People

  • Andriy I Batchinsky
  • Bryan S. Jordan
  • Corina Necsoiu
  • Dara Regn
  • Leopoldo C. Cancio
  • Michael J. Morris
  • William Federspiel

Organizations

  • United States Army Institute of Surgical Research

Tags

DTIC Thesaurus Topics

  • Acid-Base Imbalance
  • Acute Respiratory Distress Syndrome
  • Airway Management
  • Blood
  • Cardiovascular Physiological Phenomena
  • Casualties
  • Failure Mode And Effect Analysis
  • Health Services
  • Hemorrhagic Shock
  • Lung Diseases
  • Medical Evacuation
  • Respiration Disorders
  • Therapy
  • Veins
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Aerospace logistics and air mobility.
  • Cardiovascular Physiology
  • Systems Analysis and Design