Simulated Optimization of Brachytherapy for the Treatment of Breast Cancer

Abstract

This project s dual objectives are the preparation of the PI for a career in breast cancer research and the design of a system of computer-base simulations capable of evaluating the effectiveness of various methods of breast cancer brachytherapy treatments both in general and for each individual patient for use in clinical decision-making. PI was trained in the use of the ABAQUS software package to finish the Finite Element portion of the project as well as acquiring additional computing resources to facilitate and streamline the remaining parts of the project. Using these resources, models of the various treatment devices were created with manufacturer specifications and tested in an idealized tissue model of a breast demonstrating adequate similarity to documented physical behavior. Work was then started on creating breast models from patient data to reflect geometry and approximate tissue inhomogeneity. This work is still in progress.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2013
Accession Number
ADA582484

Entities

People

  • Miriam Graf

Organizations

  • University of California, San Diego

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Adipose Tissue
  • Biomedical Research
  • Breast Cancer
  • California
  • Computers
  • Geometry
  • Ionization Chambers
  • Materials
  • Monte Carlo Method
  • Neoplasms
  • Radiation
  • Radiotherapy
  • Simulations
  • Software Development
  • Standards
  • X Rays

Fields of Study

  • Medicine
  • Physics

Readers

  • Artificial Intelligence
  • Oncology and Biomarker-Based Cancer Detection.
  • Structural Health Monitoring of Composite Structures.