Family-based Exercise Intervention for Children and Adolescents with Prader-Willi Syndrome
Abstract
Physical activity (PA) holds strong potential as a non-pharmacological therapeutic approach to complement the management of Prader-Willi Syndrome (PWS). Since childhood obesity is an escalating problem associated with multiple maladies, providing alternative PA intervention strategies is vital. We have developed an at-home PA intervention titled Active Play at Home. We expect improvements in motor coordination, sensory integration, body composition, and quality of life in participants. We have enrolled 62 families at CSUF as of 9/14/2012. Our preliminary findings demonstrate high compliance (~88%) with the intervention in most participants. We have also demonstrated that the Bruininks-Oseretsky Test of Motor Proficiency is a reliable instrument to evaluate motor function in individuals with PWS. We have been able to identify seven distinct nutritional phases in individuals with PWS. We have also shown that hyperghrelinemia begins in early infancy in PWS and decreases as the individual gets older. Therefore, ghrelin is unlikely to be the "key player" in the increased appetite found in individuals with PWS.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2012
- Accession Number
- ADA582729
Entities
People
- Daniel J Driscoll
- Daniela A. Rubin
- Debra J. Rose
- Jie Weiss
- Kathleen S Wilson
- Marilyn Dumont-driscoll
Organizations
- California State University, Fullerton