Plasma-Enhanced Copolymerization of Amino Acid and Synthetic Monomers

Abstract

In this paper we report the use of plasma-enhanced chemical vapor deposition (PECVD) for the simultaneous deposition and copolymerization of an amino acid with other organic and inorganic monomers. We investigate the fundamental effects of plasma-enhanced copolymerization on different material chemistries in stable ultrathin coatings of mixed composition with an amino acid component. This study serves to determine the feasibility of a direct, facile method for integrating biocompatible/active materials into robust polymerized coatings with the ability to plasma copolymerize a biological molecule (L-tyrosine) with different synthetic materials in a dry, one-step process to form ultrathin coatings of mixed composition. This process may lead to a method of interfacing biologic systems with synthetic materials as a way to enhance the biomaterial-tissue interface and preserve biological activity within composite films.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Dec 16, 2011
Accession Number
ADA582846

Entities

People

  • Hao Jiang
  • Kyle D. Anderson
  • Rachel Jakubiak
  • Rajesh R Naik
  • Seth L. Young
  • Timothy J. Bunning
  • Vladimir V. Tsukruk

Organizations

  • Georgia Tech

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amino Acids
  • Chemical Synthesis
  • Chemical Vapor Deposition
  • Chemistry
  • Coatings
  • Composite Materials
  • Copolymerization
  • Fabrication
  • Materials
  • Materials Engineering
  • Materials Processing
  • Materials Science
  • Measurement
  • Molecules
  • Surface Properties
  • Synthetic Materials
  • Vapor Deposition

Readers

  • Polymer Science and Engineering.
  • Thin Film Deposition Science.