Targeted Approach to Overcoming Treatment Resistance in Advanced Prostate Cancer

Abstract

The purpose of this project is to determine if rescinnamine is effective against prostate cancer and treatment resistance. We found that rescinnamine is less effective against prostate cancer that against cancers from other organs. In organisms, the concentration that would effectively cause tumor growth inhibition is limited by its hypotensive activity. We are currently exploring rescinnamine derivatives that have decreased hypotensive activity, and increased tumor growth inhibition.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2013
Accession Number
ADA583043

Entities

People

  • Karin Scarpinato

Organizations

  • Georgia Southern University

Tags

DTIC Thesaurus Topics

  • Alcohols
  • Cell Line
  • Cell Physiological Processes
  • Chemical Synthesis
  • Chemistry
  • Inhibition
  • Mass Spectrometry
  • Methanols
  • Neoplasms
  • Prostate
  • Prostate Cancer
  • Resistance
  • Spectrometry

Fields of Study

  • Physics

Readers

  • Oncology (Cancer Research).