Effects of Bright Light Therapy on Sleep, Cognition, Brain Function, and Neurochemistry in Mild Traumatic Brain Injury

Abstract

Data collection is underway and preliminary findings from the first subjects to complete the study are encouraging. Overall, our preliminary data on cognition, emotion, subjective and objective sleep quality suggest that six weeks of morning Bright Blue Light therapy versus comparable Amber Light Placebo are supporting our initial hypotheses. Furthermore, initial comparisons using functional magnetic resonance imaging tasks also suggest that the Bright Blue Light condition was effective in altering brain responses during demanding attention and concentration tasks, whereas such changes were not evident in the Amber Light Placebo condition. While data are too preliminary to draw conclusions, these initial findings point toward some beneficial effects of the active treatment in reducing daytime sleepiness and sleep-related functional impairments, improving objective sleep quantity, and showing clinically significant improvements in several neuropsychological domains, as well as affecting functional brain responses.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2013
Accession Number
ADA583289

Entities

People

  • Lily Preer
  • William D. Killgore

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anxiety Disorders
  • Brain Injuries
  • Drug Abuse
  • Health Services
  • Medical Personnel
  • Neuroimaging
  • Psychiatry
  • Psychology
  • Traumatic Stress Disorder

Fields of Study

  • Medicine
  • Psychology

Readers

  • Circadian Sleep-Wake Regulation and Chronobiology
  • Neurotrauma and Rehabilitation Medicine.
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.