Continuous Synthesis of Aminophenols from Nitroaromatic Compounds by Combination of Metal and Biocatalyst

Abstract

The combined action of immobilized hydroxylaminobenzene mutase and zinc in a flow-through system catalyzes the conversion of nitroaromatic compounds to the corresponding ortho-aminophenols, including a novel analog of chloramphenicol.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2005
Accession Number
ADA585271

Entities

People

  • Heather R. Luckarift
  • Jim C. Spain
  • Lloyd J. Nadeau

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Air Force
  • Air Force Research Laboratories
  • Anti-Bacterial Agents
  • Aqueous Solutions
  • Chemical Compounds
  • Chemical Synthesis
  • Chemistry
  • Conversion
  • Efficiency
  • Enzymes
  • Flow Rate
  • Immobilized Enzymes
  • Military Research
  • Nitrobenzenes
  • Organic Chemistry
  • Substrate Specificity
  • Substrates

Fields of Study

  • Chemistry

Readers

  • Molecular and Cellular Biochemistry
  • Neurological Diseases/Conditions/Disorders