Damage Avoidance and Repair Mechanisms of Extreme Halophiles to Ionizing Radiation
Abstract
We investigated the molecular basis for ionizing radiation (IR) resistance in extremophiles using the halophilic archaeon Halobacterium salinarum as a model system and several thermophilic bacteria and archaea also highly resistant to IR. Oxidative damages are the main lesions from IR and result from the production of reactive oxygen species (ROS) via radiolysis of water.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2013
- Accession Number
- ADA585300
Entities
People
- Jocelyne DiRuggiero
Organizations
- Johns Hopkins University