Remote Control of Intact Mammalian Brain Circuits Using Pulsed Ultrasound
Abstract
We have demonstrated that pulsed ultrasound can stimulate cortical motor circuits, as well as subcortical hippocampal circuits in intake mice. The most important aspect of our work is that we have begun to gain an understanding of what properties of ultrasound waveforms make them effective for neuromodulation. The next phase of translations will include attempting to stimulate sensory regions of the brain, such as somoatosenosry cortex and auditory cortex. In parallel, we are working towards using ultrasound for cognitive modification in behaving animals. We anticipate there will be future growth in the use of ultrasound for neuromodulation based in part upon our advancements made. We expect an additional one or two manuscripts will be published in the upcoming year which were partially supported by this grant.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 31, 2012
- Accession Number
- ADA586086
Entities
People
- Brian H Smith
- William J. Tyler
Organizations
- Arizona State University