Prostate Cancer Pathology Resource Network
Abstract
The Prostate Cancer Pathology Resource Network (which has since been renamed the Prostate Cancer Biorepository Network or PCBN) is a collaboration between the Johns Hopkins School of Medicine (JHU) and the New York University School of Medicine (NYU). The PCBN has developed a biorepository with high quality, well annotated specimens that can be used by prostate cancer researchers. The specimens in the PCBN include prostatectomy tissues (frozen, paraffin embedded, and tissue microarrays (TMAs), serum, plasma, buffy coat, prostatic fluid, and derived specimens (DNA and RNA); these specimens are linked to clinical and outcome data and supported by an informatics infrastructure. The PCBN is currently made accessible to outside researchers through a website. The PCBN has been open to researchers since July 1 2011. Since that time it has been publicized at national and international meetings, surveyed prostate cancer researchers across the country for their tissue and biospecimen needs, finalized policies and procedures for access to tissue, finalized SOPs for most common processes, conducted biospecimen research on DNA and RNA best practices and presented these at international meetings, sponsored a successful workshop on biospecimen and biomarker issues for advanced prostate cancer, significantly increased the number of TMAs and specimens available, and received 35 requests for biospecimens from researchers in the US and abroad, of which 24 have been fulfilled and 11 more in process. Accrual of specimens from men with advanced or metastatic disease is an increasing focus of the PCBN.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2013
- Accession Number
- ADA586663
Entities
People
- Bruce J Trock
Organizations
- Johns Hopkins University