Modified of an Accepted Animal Model of Osteomyelitis to Simulate and Evaluate Treatment of War Extremity Wounds. Addendum

Abstract

The primary goal of this project is to evaluate the efficacy of selected antibiotic regimens in an established osteomyelitis animal model of infection from MRSA, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae. A related arm of the project at the University of Maryland-Baltimore will identify microbial gene products of the four species mentioned above with upregulated production in biofilms using two-dimensional (2D) gel electrophoresis. In addition, the PI has worked with military collaborators to publish a series of peer-reviewed manuscripts outlining guidelines for prevention and management of infections.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2012
Accession Number
ADA586835

Entities

People

  • Jason H. Calhoun

Organizations

  • Ohio State University

Tags

DTIC Thesaurus Topics

  • Chemistry
  • Debridement
  • Disability Administration
  • Health Services
  • Injury Prevention
  • Medical Personnel
  • Thoracic Injuries
  • Vaccines
  • Wounds And Injuries

Readers

  • Microbial Pathology
  • Research Science/Academic Research
  • Trauma or Military Medicine

Technology Areas

  • Biotechnology