Development of a Biosensor Nanofluidic Platform for Integration with Terahertz Spectroscopic System
Abstract
A modified configuration for a THz stage has been designed, fabricated and assembled with the final goal to combine the THz spectrometer with a microfluidic platform for characterization of biological samples in solutions. The new stage accommodates a modified optical mounting system that focuses THz radiation on micro/nanofluidic chips with reduced size of 1.5 mm x 3.0 mm for the active region, encompassing 10 sample channels in parallel. Another important improvement to the stage is modified linear positioning of the microdetector with a probe relative to the microfluidic chip in a near field configuration. A significant change in the software for computer controlled operation has also been made. We continued protocol development for spectroscopic characterization of biomaterials using micro/nanofluidic chips. The algorithm for amplitude and frequency shift corrections has been investigated and tested. The possibility to further improve spectral resolution has been demonstrated.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 30, 2013
- Accession Number
- ADA587044
Entities
People
- Aaron Moyer
- Igor Sizov
- Jerome Ferrance
- Tatiana Globus
- Tatyana Khromova
Organizations
- Vibratess (United States)