Determination of Benzalkonium Chloride in Commercial Disinfectant Formulations by Quantitative NMR Spectroscopy
Abstract
A biofouling treatment protocol for Royal Australian Navy vessels involves dosing with commercial disinfectant solutions containing the biocide benzalkonium chloride (BAC). In this work a single pulse proton Nuclear Magnetic Resonance (NMR) spectroscopic method was developed in order to permit the determination of BAC content in commercial formulations without suppression of the water resonance. The formulations were directly aliquoted into a NMR tube into which a stem coaxial insert, containing a reference solution of dimethylsulfone in deuterated lock solvent, was added. The samples were not filtered, diluted or concentrated and were quantified by comparison to a linear regression curve prepared from a commercially available standard. Eight samples from two commercial formulations were analysed with total BAC content determined to be 39-43 g/L for the Conquest formulations and 40-60 g/L for the Quatsan formulations.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 2012
- Accession Number
- ADA587297
Entities
People
- Nathan W. Mcgill
Organizations
- Defence Science and Technology Group